Chemical constituents from Vitex negundo var. heterophylla
10.7501/j.issn.0253-2670.2016.23.006
- Author:
Li-Li YU
1
Author Information
1. College of Basic Science, Jinzhou Medical University
- Publication Type:Journal Article
- Keywords:
Flavone glycosides;
Galuteolin;
Isoorientin;
Vitex Linn.;
Vitex negundo L. var. heterophylla (Franch.) Rehd.
- From:
Chinese Traditional and Herbal Drugs
2016;47(23):4151-4154
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the chemical constituents in the twigs of Vitex negundo var. heterophylla. Methods: A variety of silica gel column chromatography, Sephadex LH-20 gel column chromatography, and HPLC methods were used for the separation and purification of chemical composition. Their structures were identified on the basis of physicochemical property and spectral data. Results: Eight compounds were obtained and identified as apigenin-6-C-β-D-glucopyranosyl 8-C-α-L-arabinopyranoside (1), isoorientin (2), luteolin-6-C-α-L-arabinopyranosyl-8-C-β-D-glucopyranoside (3), luteolin-6,8-di-C-α-L-arabinopyranoside (4), apigenin-6-α-L- arabinopyranosyl-8-C-β-D-glucopyranoside (5), luteolin-6-C-α-L-arabinopyranosyl 8-C-β-L-arabinopyranoside (6), luteolin-6-C-β-L- arabinopyranosyl-8-C-β-D-glucopyranoside (7), and luteolin-7-O-β-D-glucopyranoside (8). Conclusion: Compounds 1 and 3-7 are first isolated from the plants of Vitex Linn.