Chemical constituents from flowers of Gentiana dahurica
10.7501/j.issn.0253-2670.2017.02.004
- Author:
Xiu-Yan ZHANG
1
Author Information
1. School of Pharmacy, Inner Mongolia Medical University
- Publication Type:Journal Article
- Keywords:
28-hydroxy-α-amyrin;
3β-acetoxy-28-hydroxy-12-ene-oleanane;
Flavonoids;
Flowers of Gentiana dahurica;
Terpenoids;
Ursolic acid;
β-amyrin
- From:
Chinese Traditional and Herbal Drugs
2017;48(2):241-246
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the chemical constituents of the flowers of Gentiana dahurica. Methods: All compounds were isolated and purified by silica gel, Sephadex LH-20, ODS, and MCI column chromatography. Their structures were determined by physicochemical properties and spectral data. Results: Twenty compounds were isolated from the flowers of G. dahurica. Among them, eight triterpenoids were identified as roburic acid (1), 3β-acetoxy-28-hydroxy-12-ene-oleanane (2), 28-hydroxy-α-amyrin (3), 28-hydroxy-β-amyrin (4), α-amyrin (5), β-amyrin (6), ursolic acid (7), and oleanolic acid (8). Twelve flavonoids were identified as 1-hydroxy-3,7,8-trimethoxyxanthone (9), kaempferol (10), naringenin (11), apigenin (12), luteolin (13), (2S)-naringenin-7-O-β-D- glucopyranoside (14), apigenin-7-O-β-D-glucopyranoside (15), luteolin-7-O-β-D-glucopyranoside (16), isoorientin (17), isovitexin (18), saponarin (19), and lutonarin (20). Conclusion: Seventeen compounds 1-11, 13-16, 19, and 20 are found from flowers of G. dahurica for the first time; Compounds 2-7, 9-11, 13-16, 19, and 20 are isolated from this species for the first time.
