Chemical constituents from fruits of Forsythia suspense
10.7501/j.issn.0253-2670.2017.04.005
- Author:
Xin-Jia YAN
1
Author Information
1. College of Pharmacy, Harbin University of Commerce
- Publication Type:Journal Article
- Keywords:
2-hydroxy-succinic acid 4-methylester;
4-hydroxy-4-isopropylcyclohex-1-enecarboxylic acid;
Cleroindicin C;
Forsythia Suspensa (Thunb.) Vahl.;
Glochidioboside;
Oleuropeic acid;
Senecio lactone
- From:
Chinese Traditional and Herbal Drugs
2017;48(4):644-647
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the chemical constituents from the fruits of Forsythia suspensa. Methods: Compounds were isolated by a combination of various chromatographic techniques including column chromatography over macroporous resin, Sephadex LH-20, and reversed-phase HPLC. Their structures were elucidated by physiochemical property and spectral analysis. Results: Thirteen compounds were isolated and identified as salidroside (1), forsythoside E (2), quinolacetic acid (3), rengyolone (4), senecio lactone (5), cleroindicin C (6), 4-hydroxy-4-isopropylcyclohex-1-enecarboxylic acid (7), oleuropeic acid (8), rel-(1S,2S,4S)-trihydroxy-p-menthane (9), azelaic acid (10), 2-hydroxy-succinic acid 4-methylester (11), glochidioboside (12), and (+)-isolariciresino-9-O-β-D-glucopyranoside (13). Conclusion: Compounds 5-13 are isolated from genus Forsythia Vahl. for the first time.
