A Case of Gastric CD56+ Extranodal NK/T-cell Lymphoma, Nasal Type.
- Author:
Hee Jung OH
1
;
Ki Nam SHIM
;
Ji Hyun SONG
;
Hyun Joo SONG
;
Kum Hei RYU
;
Chang Bai LEE
;
Tae Hun KIM
;
Sung Ae JUNG
;
Kwon YOO
;
Il Hwan MOON
;
Shi Nae LEE
Author Information
1. Department of Internal Medicine, Ewha Medical Research Institute, Ewha Womans University College of Medicine, Seoul, Korea. shimkn@ewha.ac.kr
- Publication Type:Case Report
- Keywords:
NK/T cell lymphoma;
Stomach
- MeSH:
Biopsy;
Female;
Fever;
Gastrointestinal Hemorrhage;
Hemorrhage;
Herpesvirus 4, Human;
Humans;
Lymphoma*;
Middle Aged;
Necrosis;
Stomach;
Stomach Ulcer
- From:Korean Journal of Gastrointestinal Endoscopy
2006;32(3):194-199
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
A NK/T cell lymphoma is highly aggressive lymphoma of a putative NK-cell origin with a predominant extranodal presentation and a rapidly fatal course. CD56 has been reported to be the most reliable marker for a NK/T cell lymphoma. A NK/T cell lymphoma is strongly associated with the Epstein-Barr virus. We report a case of an aggressive NK/T cell lymphoma presenting as a gastric ulcer. A 52-year-old female patient presented with hematochezia and fever. The endoscopic finding showed a gastric ulcer with a recent bleeding stigma. Histologically, the gastric biopsy showed a diffuse infiltration of small or medium sized lymphoma cells with an angiocentric growth pattern and necrosis. The lymphoma cells were CD56+, CD3+, CD20-, which are consistent with a NK/T cell lymphoma. Unfortunately, the patient was discharged without treatment. We report this case with a review of the relevant literature.
