Studies on sesquiterpenes from Vladimiria souliei
10.7501/j.issn.0253-2670.2017.09.003
- Author:
Bo-Lun ZHOU
1
Author Information
1. School of Traditional Chinese Medicine, Guangdong Pharmaceutical University
- Publication Type:Journal Article
- Keywords:
9-oxonerolidol;
Sesquiterpenes;
Vladimiria souliei (Franch.) Ling;
Vladimiriae Iljin;
Vlasoudide;
Vlasoudione
- From:
Chinese Traditional and Herbal Drugs
2017;48(9):1713-1718
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the sesquiterpenes from the roots of Vladimiria souliei. Methods: The compounds were isolated by silica gel, Sephadex LH-20, medium pressure chromatographic column, preparative-TLC, and preparative-HPLC. And their structures were identified by means of chemical methods and spectroscopic analyses. Results: Nine compounds were isolated from V. souliei, and named as 15-acetoxy-11αH-germacra-1(10)E, 4E-diene-12, 6α-olide (1), 15-acetoxy-11βH-germacra-1(10)E, 4E-diene-12, 6α-olide (2), 12-hydroxy-5α(H), 7α(H)-eudesm-4(14), 11(13)-diene-9-one (3), oplodiol (4), dihydroestafiatone (5), 10-oxo-dihydroxy-11β, 13-dihydrode hydrocostuslactone (6), (11S)-13-hydroxyl-guaia-4(15), 10(14)-diene-12, 6α-olide (7), 9-oxonerolidol (8), and vernopolyanthone (9). Conclusion: Compounds 1 and 3 are new compounds, named as vlasoudide and vlasoudione; and compounds 4-9 are isolated from the roots of V. souliei for the first time.
