Macro-aspartate Aminotransferase in a Patient with Chronic Hepatitis C.
- Author:
Yong Woo CHUNG
1
;
Joo Hyun SOHN
;
Chang Hee BAEK
;
Jong Pyo KIM
;
Yong Cheol JEON
;
Dong Soo HAN
;
Dong Hoo LEE
;
Choon Suhk KEE
;
Il Kyu PARK
Author Information
1. Department of Internal Medicine, Hanyang University College of Medicine, Guri, Korea. sonjh@hanyang.ac.kr
- Publication Type:Case Report ; English Abstract
- Keywords:
Chronic hepatitis C;
Macro-AST;
Macroenzyme
- MeSH:
Aspartate Aminotransferases/*blood;
Female;
Hepatitis C, Chronic/*enzymology;
Humans;
Isoenzymes/blood;
Middle Aged
- From:The Korean Journal of Gastroenterology
2006;47(3):229-232
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Macroenzymes are normal enzymes complexed with an immunoglobulin (usually IgG, rarely IgA or IgM). A number of macroenzymes have been reported in the literature. Among them, macro-AST has been detected in diseases such as acute and chronic hepatitis, various malignancies and autoimmune diseases, but usually not associated with any specific disease. We report a case of elevated AST activity in serum due to marco-AST formation in a female with chronic hepatitis C which was confirmed by AST isoenzyme electrophoresis. To our knowledge, this is the first report of macro-AST occurred in chronic hepatitis patient in Korea.
