Research progress on chemical constituents and pharmacological activities of Bufonis Venenum
10.7501/j.issn.0253-2670.2017.12.033
- Author:
Ying-Lan CHEN
1
Author Information
1. School of Pharmacy, Shanghai University of Traditional Chinese Medicine
- Publication Type:Journal Article
- Keywords:
Antimicrobial effect;
Antitumor effect;
Bufadienolide;
Bufonis Venenum;
Cardiac effect;
Indolealkylamine;
Sterol
- From:
Chinese Traditional and Herbal Drugs
2017;48(12):2579-2588
- CountryChina
- Language:Chinese
-
Abstract:
Bufonis Venenum, as an important Chinese traditional natural medicine, has complex chemical composition and has been widely used in clinical treatment with significant effects. The chemical constituents in Bufonis Venenum mainly included bufadienolides, indole alkaloids, steriods, etc. With the further research on Bufonis Venenum both at home and abroad, its chemical composition and mechanism of pharmacological activities have been more and more clearly, especially in the aspects of narcotic analgesic, cardiac, and antitumor therapy. This paper reviewed the chemical composition and pharmacology advances of Bufonis Venenum in order to provide reference to clinical use.
