Sesquiterpenes constituents from fruits of Michelia yunnanensis
10.7501/j.issn.0253-2670.2017.13.004
- Author:
Lin-Fen DING
1
Author Information
1. School of Pharmaceutical Science and Yunnan Key Laboratory of Pharmacology for Natural Products, Kunming Medical University
- Publication Type:Journal Article
- Keywords:
11,13-dehydro-compressanolide;
9-oxonerolidol;
Costunolide;
Lanuginolide;
Michelia yunnanensis Franch. ex Finet et Gagn;
Parthenolide
- From:
Chinese Traditional and Herbal Drugs
2017;48(13):2608-2613
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the chemical constituents from fruits of Michelia yunnanensis. Methods: The chemical constituents were isolated and purified by column chromatographies on silica gel and Sephadex LH-20. Their structures were elucidated on the basis of spectroscopic data. Results: Twelve compounds were isolated from methanol extract of the fruits of M. yunnanensis and the structures were identified as 13-methoxy-11β, 13-dihydrocostunolide (1), lanuginolide (2), tulipinolide (3), lipiferolide (4), costunolide (5), parthenolide (6), 11β, 13-dihydroparthenolide (7), 4α, 5β-epoxy-13-methoxy-11βH-germacra-1 (10)-en-12, 6α-olide (8), cyperusol C (9), aromadendra-4β, 10α-diol (10), 9-oxonerolidol (11), and 11, 13-dehydrocompressanolide (12). Conclusion: Compound 1 is isolated as a new natural product. 1H-NMR and 13C-NMR data of compounds 1 and 2 are reported for the first time. Except compound 6, other compounds are isolated from this plant for the first time.
