Chemical constituents from Pinus yunnanensis
10.7501/j.issn.0253-2670.2017.18.005
- Author:
Jian-Hua MIN
1
Author Information
1. Lizhu Pharmaceutical Co., Ltd.
- Publication Type:Journal Article
- Keywords:
5-O-β-D-glucopyranosylthymoquinol;
Icariside E4;
Isopimarinol;
Pinocembrin;
Pinus yunnanensis Lamb.
- From:
Chinese Traditional and Herbal Drugs
2017;48(18):3693-3697
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the chemical constituents of Pinus yunnanensis. Methods The whole plant of air-dried P. yunnanensis was extracted with methnol. The methnol extract was suspended in H2O and extracted with petroleum, ethyl acetate, and n-BuOH, successively. The compounds were isolated and purified by column chromatography from the petroleum and ethyl acetate fractions, and identified based on spectral analyses (MS, 1D- and 2D-NMR, IR, UV). Results Fourteen compounds were isolated from P. yunnanensis and characterized as (7R,8R)-7,8-dihydro-3'-hydroxyl-7-(4-hydroxyl-3-methoxyphenyl)-8-hydroxymethyl-1'-benzofuranpropanol- 4-O-(3-O-methyl-α-L-rhamnopyranoside) (1), pinosylvine (2), stigmast-4-en-3-one (3), kaempferol (4), isopimarinol (5), quercetin (6), pinocembrin (7), taxifilin (8), 3-hydroxyl-5-methoxy-stilbene (9), 5-O-β-D-glucopyranosyl-thymoquinol (10), icariside E4 (11), 3,4-dimethoxyphenyl-1-O-β-D-glucopyranoside (12), schizandriside (13), and β-stitosterol (14). Conclusion Compounds 1, 3-7, and 10-13 are obtained from Pinus yunnanensis Lamb. for the first time.