Chemical constituents of Glechoma longituba
10.7501/j.issn.0253-2670.2017.20.014
- Author:
Ren-Geng SHU
1
Author Information
1. School of Pharmacy, Jiangxi University of Traditional Chinese Medicine
- Publication Type:Journal Article
- Keywords:
Emodin;
Glechoma longituba (Nakai) Kupr.;
Loliolide;
Syringic acid;
Ursolic acid
- From:
Chinese Traditional and Herbal Drugs
2017;48(20):4215-4218
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the chemical constituents of Glechoma longituba. Methods Chemical constituents were extracted by organic solvents, isolated and purified by chromatographic techniques with silica gel, Sephadex LH-20, semi-preparative HPLC, and recrystallization. Their structures were elucidated on the basis of physiochemical and spectral analyses. Results Thirteen compounds were obtained and elucidated as ursolic acid (1), asoleanolic acid (2), protocatechualdehyde (3), betulic acid (4), luteolin (5), β-sitosterol (6), lutin (7), syringic acid (8), 4-acetoxy-3,5-dimethoxybenzoicacid (9), 2,5-dihydroxy-1,4-benzenedicarboxylic acid (10), (E)-3-[4-(carboxymethoxy)-3-methoxyphenyl] acrylic acid (11), emodin (12), and loliolide (13). Conclusion Compounds 8-10 and 12 are isolated from this plant for the first time. Compounds 11 and 13 are isolated from the plants of Glechoma Linn. for the first time.