Application progress on nanosuspension based gel in transdermal drug delivery of Chinese materia medica
10.7501/j.issn.0253-2670.2017.23.030
- Author:
Bao-De SHEN
1
Author Information
1. Key Lab of Modern Preparation of Traditional Chinese Medicine (TCM), Ministry of Education, Jiangxi University of TCM
- Publication Type:Journal Article
- Keywords:
Bioavailability;
Chinese materia medica;
Gel mechanism;
Nanosuspension based gel;
Transdermal drug delivery
- From:
Chinese Traditional and Herbal Drugs
2017;48(23):5012-5018
- CountryChina
- Language:Chinese
-
Abstract:
Nanosuspension based gel (NS-gel) is molecular gel based on nanosuspension system. NS-gel is developed by incorporating nanosuspension or nano powders obtained by solidification of nanosuspension with gel matrix and other excipients, which has dual advantages of nanosuspension and gel. This paper reviews the preparation and evaluation of NS-gel, the factors influencing the transdermal absorption of NS-gel and its application progress in transdermal drug delivery of Chinese materia medica (CMM), and analyzes the problems of NS-gel research, so as to provide reference and thinking for the further study and development of NS-gel in transdermal drug delivery of CMM.
