Study on lignan constituents from aerial part of Rubia cordifolia
10.7501/j.issn.0253-2670.2017.23.006
- Author:
Mao-Ting ZHANG
1
Author Information
1. College of Pharmacy, Anhui University of Chinese Medicine
- Publication Type:Journal Article
- Keywords:
(-)-episyringaresinol;
(-)-secoisolariciresinol;
(7S,8R)-dihydrodehydroconiferyl alcohol;
Burselignan;
Lignans;
Rubia cordifolia L.
- From:
Chinese Traditional and Herbal Drugs
2017;48(23):4856-4859
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the chemical constituents of the aerial part of Rubia cordifolia. Methods All compounds were isolated and purified by silica gel, Sephadex LH-20, and MCI column chromatography. Their structures were determined by physicochemical properties and spectral data. Results Eleven compounds were isolated and identified as: (-)-episyringaresinol (1), (-)-secoisolariciresinol (2), (-)-3,4-divanillyl tetrahydrofuran (3), lignans (+)-demethoxypinoresinol (4), (+)-syringaresinol (5), (+)-isolariciresinol (6), burselignan (7), (7S,8R)-dihydrodehydroconiferyl alcohol (8), 4,5'-dimethoxy-lariciresinol (9), (+)-7R,8S-5- methoxydihydrodehydroconifery alcohol (10), and 5,5'-dimethoxy-7-oxolariciresinol (11). Conclusion All compounds are isolated from this plant for the first time.