Chemical constituents from stems and leaves of Mappianthus iodoides
10.7501/j.issn.0253-2670.2018.02.004
- Author:
Zhi-Hua JIANG
1
Author Information
1. School of Pharmacy, Fujian University of Traditional Chinese Medicine
- Publication Type:Journal Article
- Keywords:
Dehydrodiconiferyl alcohol;
Icacinaceae;
Lariciresinol;
Lignans;
Loliolide;
Mappianthus iodoides Hand. -Mazz.;
Norsesquiterpenoids;
Olivil
- From:
Chinese Traditional and Herbal Drugs
2018;49(2):282-287
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the chemical constituents of the stems and leaves of Mappianthus iodoides. Methods The chemical constituents of M. iodoides were separated and purified by silica gel, ODS, Sephadex LH-20 gel column chromatographies, and preparative HPLC. Their structures were identified by physicochemical properties, spectroscopic analysis, as well as comparisons with the data reported in literature. Results Sixteen compounds were isolated from the 90% ethanol extract of the stems and leaves of M. iodoides, which were identified as 9-hydroxy-4,6-megastigmadien-3-one (1), 9-hydroxy-4,7-megastigmadien-3-one (2), blumenol A (3), 9,10-dihydroxy-4,7-megastigmadien-3-one (4), 5,12-epoxy-9-hydroxy-7-megastigmen-3-one (5), 5,12-epoxy-6,9-hydroxy-7- megastigmen-3-one (6), loliolide (7), lariciresinol (8), isolariciresinol (9), 5′-methoxylariciresinol (10), olivil (11), dehydrodiconiferyl alcohol (12), chushizisin I (13), 3,3-didemethoxyverrucosin (14), 4-epi-larreatricin (15), and glycerol monolinoleate (16). Conclusion All compounds are isolated from the genus Mappianthus for the first time.
