LC-MS/MS-based molecular networking producing enlighten study of Chinese materia medica
10.7501/j.issn.0253-2670.2018.02.001
- Author:
Tao-Fang CHENG
1
Author Information
1. School of Pharmacy, Shanghai Jiao Tong University
- Publication Type:Journal Article
- Keywords:
Chinese materia medica;
Global Natural Products Social Molecular Networking (GNPS);
LC-MS/MS;
Molecular networking;
Traditional Chinese medicine
- From:
Chinese Traditional and Herbal Drugs
2018;49(2):265-273
- CountryChina
- Language:Chinese
-
Abstract:
Recently, LC-MS/MS-based molecular networking has been widely used in the field of natural products from microorganisms, marine organisms, fungi, plants, and so on, while there are few reports on the research and application of LC-MS/MS-based molecular networking in the field of Chinese materia medica (CMM). Covering molecular networking topic, what is molecular networking was firstly introduced and the literatures related to molecular networking was retrieved. Then the application of molecular networking on five aspects were reviewed, including qualitative characterization of components, quantitative characterization of components and quality control, guiding the active compounds separation, optimizing the extraction process and disease diagnosis as well as personalized treatment. In the end, this study forecasted the prospects of molecular networking in the field of CMM, aiming to provide new thought and methodology for the research of CMM and expect to expedite the development of traditional Chinese medicine.
