Chemical constituents from whole herbs of Corydalis edulis
10.7501/j.issn.0253-2670.2018.07.004
- Author:
Ling-Hui CHAO
1
Author Information
1. Modern Research Center for Traditional Chinese Medicine, School of Chinese Materia Medica, Beijing University of Chinese Medicine
- Publication Type:Journal Article
- Keywords:
6, 7-dimethoyisoquinolin-1 (2H)-one;
6, 7-methylenedioxydihydroisocoumarin;
Corydalis edulis Maxim.;
Lignan;
Quinolone
- From:
Chinese Traditional and Herbal Drugs
2018;49(7):1508-1512
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the chemical constituents from the herbs of Corydalis edulis. Methods: The compounds were isolated and purified by various column chromatographies, and their structures were identified by physiochemical properties and spectroscopic data. Results: Fifteen compounds were isolated from the n-BuOH layer of EtOH extract of the herbs of C. edulis. and identified as 6, 7-methylenedioxydihydroisocoumarin (1), oxohydrastinine (2), 6, 7-dimethoyisoquinolin-1 (2H)-one (3), 6, 7-methylenedioxy-1 (2H)-isoquinolinone (4), (+)-syringaresinol (5), (+)-medioresinol (6), salidroside (7), isosalicin (8), icariside D2 (9), salicin (10), icariside F2 (11), icariside B2 (12), nicotinamide (13), pyrocatechol (14), and 5-hydroxyl-2-hydroxymethylpyridine (15), respectively. Conclusion: Compound 1 is a new natural product. Compounds 3, 5-12, 14, and 15 were isolated from Corydalis species for the first time. Compounds 2, 4, and 13 were firstly obtained from C. edulis.
