Chemical constituents from fruit pedicels of Panax ginseng
10.7501/j.issn.0253-2670.2018.08.003
- Author:
Wenjing HAN
1
Author Information
1. Beijing Key Laboratory of Plant Resources Research and Development, Beijing Technology and Business University
- Publication Type:Journal Article
- Keywords:
(20S,23E)-dammar-23-ene-3β,6α,12β,20,25-pentol;
20(R)- dammar-3-one-6α,12β,20,25-tetrol;
Fruit pedicels;
Ginsenoside Y;
Ginsenosides;
Panax ginseng C. A. Meyer
- From:
Chinese Traditional and Herbal Drugs
2018;49(8):1751-1760
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the chemical constituents of the fruit pedicels of Panax ginseng. Methods The compounds were purified by silica gel column chromatography and preparative reverse-phase high performance liquid chromatography. Their structures were elucidated on the basis of spectroscopic analyses. Results Twenty-eight compounds were isolated from the total extract of the fruit pedicels of P. ginseng. They were identified as 20(S)-protopanaxatriol (1), 20(S)-protopanaxadiol (2), 20(S)-dammar-24- ene-3-one-6α,12β,20-triol (3), (20S,23E)-dammar-23-ene-3β,6α,12β,20,25-pentol (4), (20S,24R)-dammar-26-ene-3β,6α,12β,20,24- tetrol (5), 20(R)-dammar-3-one-6α,12β,20,25-tetrol (6), ginsenoside Rk2 (7), 20(R)-dammar-24(25)-epoxy-3β,6α,12β,20- tetrol (8), ginsenoside CK (9), 20(S)-dammar-3β,6α,12β,20,25-pentol (10), ginsenoside Rh4 (11), 20(S)-dammar-3β,12β,20,25-tetrol (12), 20(S)-dammar-3β,6α,12β,20,24-pentol (13), 20(R)-dammar-3β,6α,12β,20,25-pentol (14), pseudoginsenoside RT5 (15), ginsenoside Rh1 (16), ginsenoside Rh3 (17), 20(S)-dammar-3β,12β,20,25-tetrol-3-O-β-D-glucopyranoside (18), 20(S)-isoginsenoside Rh3 (19), ginsenoside Rg1 (20), ginsenoside Y (21), ginsenoside Rd (22), ginsenoside la (23), 20(S)-dammar-3β,12β,20,25-tetrol-3-O-β-D-glucopyranosyl-(1→2)-O-β-D-glucopyranoside (24), ginsenoside Rg2 (25), notoginsenoside Fe (26), ginsenoside Re (27), and ginsenoside Rb1 (28), respectively. Conclusion Among them, compounds 4-6, 8, 10, 12, 13, and 21 are isolated from P. ginseng for the first time.
