A new sesquiterpenoid from Artemisia lavandulaefolia
10.7501/j.issn.0253-2670.2018.09.003
- Author:
Lin-Fen DING
1
Author Information
1. Yunnan Key Laboratory of Pharmacology for Natural Products, School of Pharmaceutical Science, Kunming Medical University
- Publication Type:Journal Article
- Keywords:
5-epi-eudesma-4(15)-ene-1β,6β-diol;
Artemilavanone A;
Artemisia lavandulaefolia DC.;
Espeletone;
Scopoletin;
Sesquiterpenoid
- From:
Chinese Traditional and Herbal Drugs
2018;49(9):1995-1999
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the chemical constituents from the aerial parts of Artemisia lavandulaefolia. Methods The constituents were isolated and purified by various column chromatographic techniques, and their structures were identified by spectroscopic analysis. Results Eleven compounds were isolated from 95% ethanol aqueous extract of A. lavandulaefolia and the structures were identified as (4R,5R,7R,10R)-4-hydroxy-eudesma-2,11-dien-1-one (1), 5-epi-eudesma-4(15)-ene-1β,6β-diol (2), eudesma-4(15)-ene-1β,6α-diol (3), methyl 3-oxo-eudesma-1,4,11(13)-trien-12-oate (4), 11β,13-dihydrosantamarin (5), anthemidin (6), scopoletin (7), paeonol (8), ethyl caffeate (9), espeletone (10), and (1R*,2S*,3S*,4S*)-mentha-1,2,3,4-tetrol (11). Conclusion Compound 1 is a new compound named artemilavanone A, and compounds 2-11 are isolated from this plant for the first time.