Advances in treatment of atrial fibrillation with Chinese materia medica and biological molecular network analysis of ginsenoside in treating atrial fibrillation
10.7501/j.issn.0253-2670.2018.12.007
- Author:
Bao-Chen ZHU
1
Author Information
1. Beijing University of Chinese Medicine
- Publication Type:Journal Article
- Keywords:
Apoptosis;
Atrial fibrillation;
Biological molecular network analysis;
Blood components;
Ginsenoside
- From:
Chinese Traditional and Herbal Drugs
2018;49(12):2769-2774
- CountryChina
- Language:Chinese
-
Abstract:
Atrial fibrillation (AF) is the most common type of arrhythmia in clinic. At present, the therapies of AF by western medicine are fewer with obvious side effects. It is expected to improve the curative effect and reduce side effects by the combination of traditional Chinese medicine (TCM) and western medicine. The research progresses of Chinese materia medica (CMM) treatment for AF were summarized, and the biological molecular network was carried out for the analysis of blood components of ginsenoside from the key CMM Panax ginseng in AF treatment. The blood components of ginsenoside in network analysis including targets searching, network construction, and GO biological processes analysis were selected to explore the possible mechanism in treating AF. It indicated that the possible mechanism might be related to apoptosis regulation, cell membrane potassium ion flow, and so on.
