Development, measurement, and application of biopharmaceutics classification system for Chinese materia medica
10.7501/j.issn.0253-2670.2018.12.003
- Author:
Xiu-Qing WANG
1
Author Information
1. Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences
- Publication Type:Journal Article
- Keywords:
Biopharmaceutics classification system;
Chinese materia medica;
Multi-component;
Permeability;
Solubility
- From:
Chinese Traditional and Herbal Drugs
2018;49(12):2742-2748
- CountryChina
- Language:Chinese
-
Abstract:
Biopharmaceutics classification system (BCS) is a research method that scientifically classifies drugs based on its solubility and permeability, which is generally applicable to oral chemical products of single-component. Compared with most western medicines, Chinese materia medica (CMM) has a complex system of multiple components, so BCS has certain limitations in the study of CMM. Based on the scientific framework of BCS, domestic scholars have successively proposed some BCS for CMM. This article reviews the development, determination, and application of BCS for CMM by consulting relevant domestic and foreign literatures, in order to lay a reference for the in-depth research of BCS for CMM.
