Research progress on chemical constituents and artificial synthesis of Bufonis Venenum
10.7501/j.issn.0253-2670.2018.13.034
- Author:
Chong-Feng SUN
1
Author Information
1. Shandong Hongjitang Pharmaceutical Co., Ltd.
- Publication Type:Journal Article
- Keywords:
Anti-inflammatory;
Antitumor;
Artificial synthesis;
Bufadienolides;
Bufonis Venenum;
Cardiac effect;
Indole alkaloids
- From:
Chinese Traditional and Herbal Drugs
2018;49(13):3183-3192
- CountryChina
- Language:Chinese
-
Abstract:
Bufonis Venenum, as a precious Chinese materia medica, has complex chemical constituents and has been widely used in clinical treatment with significant effects. The chemical constituents in Bufonis Venenum mainly included bufadienolides, indole alkaloids, and steroids, etc. Modern pharmacological research has demonstrated its antitumor, cardiac, anti-inflammatory, and narcotic analgesic, etc. This paper reviewed the chemical constituents, pharmacological activity, and artificial synthesis of Bufonis Venenum, providing theoretical reference for material basic research, pharmacodynamic mechanism interpretation, development, and utilization.
