Chemical components from Lianhua Qingwen Capsules (II)
10.7501/j.issn.0253-2670.2018.14.005
- Author:
Chuang-Feng ZHANG
1
Author Information
1. Beijing Yiling Pharmaceutical Co., Ltd.
- Publication Type:Journal Article
- Keywords:
Aloe-emodin-8-O-β-D-glucopyranoside;
Caffeic acid ethyl ester;
Lianhua iridoid A;
Lianhua Qingwen Capsules;
Liquiritin apioside
- From:
Chinese Traditional and Herbal Drugs
2018;49(14):3222-3225
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the chemical constituents of Lianhua Qingwen Capsules. Methods: The compounds were isolated and purified by gel column chromatography, MPLC, and preparative HPLC from 50% ethanol fraction of macroporous resin column chromatography of Lianhua Qingwen crude extracts. Their structures were elucidated by the spectral analyses. Results: Eight compounds were isolated and identified as 10-O-(p-hydroxycinnamoyl)-adoxosidic acid (1), aloe-emodin-8-O-β-D-glucopyranoside (2), quercitrin (3), matairesinol-4’-O-β-D-glucoside (4), liquiritin apioside (5), epi-vogeloside (6), vogeloside (7), and caffeic acid ethyl ester (8). Conclusion: Compound 1 is a new compound named lianhua iridoid A. Compounds 5-8 are isolated from Lianhua Qingwen Capsules for the first time. This study provides substance foundation for chemical research of Lianhua Qingwen Capsules.
