Research progress on pharmacological effects of p-coumaric acid
10.7501/j.issn.0253-2670.2018.17.030
- Author:
Xi-Qin GUAN
1
Author Information
1. College of Pharmacy, Shandong University of Traditional Chinese Medicine
- Publication Type:Journal Article
- Keywords:
Anti-inflammation;
Anti-oxidant activity;
Antitumor;
Cardiovascular protective effect;
Diabetes;
P-coumaric acid
- From:
Chinese Traditional and Herbal Drugs
2018;49(17):4162-4170
- CountryChina
- Language:Chinese
-
Abstract:
p-coumaric acid is mainly found in fruits, vegetables, grains, and fungi, and is also abundant in Chinese herbal medicines. The pharmacological effects of p-coumaric acid has anti-oxidant, anti-inflammatory, immunomodulatory, antitumor effects, antiplatelet aggregation, cardiovascular protection, prevention and improvement of diabetes, and neuroprotection, while the anti-oxidant activities of p-coumaric acid is the important basis of other pharmacological effects. In addition, p-coumaric acid has a certain inhibitory effect on bacteria, and also can inhibit melanin formation and delay skin aging. This paper reviews the main pharmacological effects of p-coumaric acid and provides reference for the development of both medicinal and food resources.
