Lignans from seeds of Lepidium apetalum
10.7501/j.issn.0253-2670.2018.17.002
- Author:
Meng LI
1
Author Information
1. Henan University of Chinese Medicine
- Publication Type:Journal Article
- Keywords:
(-)-isolariciresinol;
Lepidium apetalum Willd;
Lepidiumlignan A;
Lepidiumlignan B;
Lignan
- From:
Chinese Traditional and Herbal Drugs
2018;49(17):3981-3986
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the chemical constituents from the seeds of Lepidium apetalum. Methods Compounds were isolated from the water extract from the seeds of L. apetalum by using Diaion HP-20, Toyopearl HW-40, MCI Gel CHP-20, ODS, Silica gel chromatography and semi-preparative-HPLC. Results Nine compounds were isolated and identified as lepidiumlignan A (1), lepidiumlignan B (2), erythro-1-(4-O-β-D-glucopyranosyl-3-methoxyphenyl)-2-[4-(3-hydroxypropyl)-2,6-dimethoxyphenoxy]-1,3- propanediol (3), (7R,7’E,8S)-4,9-dihydroxy-3,3’,5-trimethoxy-4’,7-epoxy-8,5’-neolign-7’-en-9’-oic acid (4), spicatolignan B (5), (-)-pinoresinol-4-O-β-D-glucopyranoside (6), (-)-isolariciresinol (7), aegineoside (8), and (+)-syringaresinol-O-β-D-glucopyra- noside (9). Conclusion Compounds 1 and 2 are new compounds, named as lepidiumlignan A and lepidiumlignan B. Compounds 3-9 are isolated from the plants for the first time.
