Isolation and identification of chemical constituents from extract of salvia polyphenolic acids
10.7501/j.issn.0253-2670.2018.21.011
- Author:
Jie-Feng TIAN
1
Author Information
1. TCM Research Center, Tasly Academy, Tasly Holding Group Co., Ltd.
- Publication Type:Journal Article
- Keywords:
Lithospermic acid;
Protocatechuic aldehyde;
Rosmarinic acid;
Salvia polyphenolic acids;
Salvianolic acid D;
Salvianolic acid D lactone
- From:
Chinese Traditional and Herbal Drugs
2018;49(21):5024-5028
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the chemical constituents from salvia polyphenolic acids. Methods Various column chromatographic techniques were used to separate and purify the chemical constituents and their structures were identified by spectral analysis. Results Seven compounds were isolated and obtained from salvia polyphenolic acids, which were identified as (2R)-2-[(3-(7-hydroxy-2-oxo-2,3-dihydrobenzofuran-4-yl)-(2E)-acryloyl) oxy]-3-(3,4-dihydroxyphenyl)-propanoic acid (1), salvianolic acid D (2), protocatechuic aldehyde (3), rosmarinic acid (4), lithospermic acid (5), salvianolic acid B (6), and salvianolic acid Y (7). Conclusion Compound 1 is a new compound, which is named as salvianolic acid D lactone.