Research ideas and progress on screening and identification of pharmacodynamic substance of Chinese materia medica
10.7501/j.issn.0253-2670.2018.22.001
- Author:
Xiao-Lin BI
1
Author Information
1. Nanjing University of Chinese Medicine
- Publication Type:Journal Article
- Keywords:
Chinese materia medica (CMM);
CMM compound;
Pharmacodynamic material basis;
Research ideas and methods;
Screening and identification of pharmacodynamic substance of CMM
- From:
Chinese Traditional and Herbal Drugs
2018;49(22):5229-5234
- CountryChina
- Language:Chinese
-
Abstract:
Study on the pharmacodynamic material basis of Chinese materia medica (CMM) is the key and difficult points of CMM research due to its complicated components and synergistic effect of multiple pathways and multiple targets in pharmacological action. Currently, research ideas and research methods of the pharmacodynamic material basis of CMM are being constantly innovated. In this review, research ideas and progress on screening and identification of pharmacodynamic substance of CMM were summarized. It suggested that the research model of interdisciplinarity, multi-dimensional screening and evaluation should be established, in order to provide references for further and comprehensively revealing the mechanism of action of CMM and the law of compatibility, and establishing quality evaluation system of CMM.