Chemical constituents from ethyl acetate extract of Gleditsiae Spina
10.7501/j.issn.0253-2670.2018.23.005
- Author:
Man QI
1
Author Information
1. College of Pharmacy, Henan University of Chinese Medicine
- Publication Type:Journal Article
- Keywords:
(-)-syringaresinol;
(2R*,3R*,4S*)-2,3-diguaiacyl-4-hydroxyl tetrahydrofuran;
Gleditsia sinensis Lam.;
Gleditsiae Spina;
Protocatechuic aldehyde;
juglanin D
- From:
Chinese Traditional and Herbal Drugs
2018;49(23):5510-5515
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the chemical constituents from the ethyl acetate extract of Gleditsiae Spina. Methods The chemical constituents were isolated and identified by chromatography on silica gel, Toyopearl HW-40C, Sephadex LH-20, MCI Gel CHP-20, ODS, and RP-HPLC. Their structures were elucidated on the basis of physicochemical properties and spectral analyses. Results Eighteen compounds were isolated from the ethyl acetate extract of Gleditsiae Spina, and identified as scopoletin (1), (-)-(7R,8S)-erythro-guaiacylglycerol (2), 5-methoxy-guaiacylglycerol (3), (-)-(7R,8R)-threo-guaiacylglycerol (4), 3,4’- dihydroxypropiophenone (5), dihydroferulic acid (6), p-hydroxybenzoic acid (7), indole-3-carbaldehyde (8), protocatechuic acid methyl (9), protocatechuic aldehyde (10), syringic acid (11), 2-guaiacylpropane-1,3-diol (12), (2R*,3R*,4S*)-2,3-diguaiacyl-4- hydroxyl tetrahydrofuran (13), 3-(2-oxopropyl)-3-hydroxy-indolin-2-one (14), juglanin D (15), C-veratroylglycol (16), 3-(4-hydroxyl-3-methoxyphenyl)-propan-1,2-diol (17), and (-)-syringaresinol (18). Conclusion Eighteen compounds are isolated from this plant for the first time.
