Pharmacological research progress of sodium ferulate in cardio-cerebral vascular disease
10.7501/j.issn.0253-2670.2019.03.034
- Author:
Li-Xia WANG
1
Author Information
1. Institute of Chemistry, Chinese Academy of Sciences
- Publication Type:Journal Article
- Keywords:
Anti-oxidativity;
Antithrombosis;
Arachidonic acid;
Cardiovascular disease;
Endothelin antagonist;
Sodium ferulate;
Thrombocytopenia aggregation
- From:
Chinese Traditional and Herbal Drugs
2019;50(3):772-777
- CountryChina
- Language:Chinese
-
Abstract:
Sodium ferulate is the sodium salt of ferulic acid, an extract of traditional Chinese herbal medicines for promoting blood circulation and detoxification, and it is rich in sources, with few side effects and high safety. Sodium ferulate has many pharmacological effects, which is a cardiovascular drug researched and developed independently in China. It was first approved in 1990 for the clinical treatment of cardiovascular diseases. In recent years, the clinical application of sodium ferulate has become increasingly widespread, and the research field is continuously expanding. Sodium ferulate is effective in treating respiratory diseases, diabetes and complications, and protecting the liver and kidney from damage. Meanwhile it has been widely used in cardiovascular diseases. Here we reviewed the research status of the prominent pharmacological effects of sodium ferulate on cardiovascular diseases in the past 30 years, mainly focusing on the antithrombotic effects, the protection of blood vessels, and the anti-oxidative effect of sodium ferulate. It is expected to provide guidance for clinical applications of sodium ferulate.
