Therapeutic effect of Ofloxacin Ear Drops combined with Bairui Granules on acute suppurative otitis media in children
10.7501/j.issn.0253-2670.2019.03.022
- Author:
Peng ZHAO
1
Author Information
1. Qinhuangdao City Chinese Medicine Hospital
- Publication Type:Journal Article
- Keywords:
Acute suppurative otitis media;
Bairui Granules;
Children;
Integrated Chinese and Western medicine;
Ofloxacin ear drops
- From:
Chinese Traditional and Herbal Drugs
2019;50(3):681-684
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the curative effect of ofloxacin ear drops combined with Bairui Granules on acute suppurative otitis media in children. Methods: A total of 186 pediatric patients with acute suppurative otitis media treated in Qinhuangdao City Chinese Medicine Hospital were divided into the treatment group and control group according to the random number table method. In the treatment group, 94 patient were treated with 0.3% ofloxacin ear drops combined with Bairui Granules. In the control group, children in the 92 cases only received ofloxacin ear drops (2-3 times a day, 6-10 drops each time; After ear dropping, taking 10 min ear bath). Each group was treated 7-10 d. The curative effect and adverse reactions were observed. Results: The total effective rate of the treatment group was 94.68% and the control group was 82.61%, there was a significant difference between the two groups. (P < 0.05). The improvement in symptom and physical scores of the treatment group was significantly better than that of the control group (P < 0.05). There was no significant difference in the incidence of adverse reactions between two groups. Conclusion: The ofloxacin ear drops can efficiently improve clinical symptoms of the patients with acute suppurative otitis media, and Bairui Granules have antipyretic and antiphlogistic effect. The combination of the two drugs had significant curative effect on acute suppurative otitis media in children with low adverse reactions incidence, so we conclude that it is worthy to be promoted.
