Chemical constituents from stems and leaves of Artabotrys hongkongensis
10.7501/j.issn.0253-2670.2019.03.003
- Author:
Qing WEN
1
Author Information
1. College of Pharmacy, Fujian University of Traditional Chinese Medicine
- Publication Type:Journal Article
- Keywords:
Alkaloids;
Annonaceae;
Artabotrys hongkongensis Hance;
Fatty acid;
Loliolide;
Sesquiterpenes;
Uvarigranol B
- From:
Chinese Traditional and Herbal Drugs
2019;50(3):551-556
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the chemical constituents from the stems and leaves of Artabotrys hongkongensis. Methods: The chemical constituents of A. hongkongensis were separated and purified by silica gel, ODS, Sephadex LH-20 gel column chromatography, and preparative HPLC. Their chemical structures were identified by physicochemical properties and spectral data. Results: A total of 16 compounds were isolated from the 90% ethanol extract of the stems and leaves of A. hongkongensis, which were identified as melilotocarpan A (1), medicarpin (2), 5,7,8-trimethoxyflarone (3), 2’-hydroxy-3’,4’,6’-trimethoxychalcone (4), piperolactam C (5), uvarilactam (6), artacinatine (7), p-coumaroyl-β-phenethylamine (8), artapilosol A (9), uvarigranol B (10), 1,6-desoxypipoxide (11), 1β,11-dihydroxy-5-eudesmen (12), loliolide (13), 4-hydroxy-3-methoxybenzaldehy (14), syringlaldehyde (15), and rabdosia acid A (16). Conclusion: All compounds are isolated from A. hongkongensis for the first time. In addition to compounds 2, 7, and 9, the other compounds are isolated from the genus Artabotrys for the first time.
