Chemical constituents from Hypericum monogynum
10.7501/j.issn.0253-2670.2019.04.002
- Author:
Xiao-Shi XU
1
Author Information
1. College of Pharmacy, South-Central University for Nationalities
- Publication Type:Journal Article
- Keywords:
2-hydroxydiplopterol;
Betulinic acid;
Hypericum monogynum L.;
Hypermongone A;
Steroids;
Triterpenoids
- From:
Chinese Traditional and Herbal Drugs
2019;50(4):798-801
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the chemical constituents of Hypericum monogynum. Methods: The chemical constituents were isolated and purified by solvent extraction method, the normal and reverse phase silica gel column chromatography and semi-preparative high performance liquid chromatography. Results: Six compounds were isolated from the chloroform extract of H. monogynum. Their structures were identified as hypermongone A (1), β-sitosterol (2), 5α,8α-epidioxyergosta-6,22-dien-3β-ol (3), isocudraniaxanthone B (4), betulinic acid (5), and 2-hydroxydiplopterol (6) by the physicochemical properties and modern spectroscopic methods. Conclusion: Compound 1 is a new compound, and compounds 3, 4, and 6 are isolated from H. monogynum for the first time.
