The Effect of the Spinal Block Level on the Requirements of Propofol for Sedation.
10.4097/kjae.2006.50.6.642
- Author:
Il Woo SHIN
1
;
Ji Eun GO
;
Kyeong Eon PARK
;
Ju Tae SOHN
;
Young Kyun CHUNG
;
Heon Keun LEE
Author Information
1. Department of Anesthesiology and Pain Medicine, College of Medicine, Gyeongsang National University, Jinju, Korea. ane1959@hanmail.net
- Publication Type:Original Article ; Randomized Controlled Trial
- Keywords:
bispectral index;
hypnosis;
propofol;
spinal anaesthesia
- MeSH:
Adult;
Anesthesia, Spinal;
Bupivacaine;
Conscious Sedation;
Head-Down Tilt;
Humans;
Hypnosis;
Hypnotics and Sedatives;
Propofol*;
Prospective Studies
- From:Korean Journal of Anesthesiology
2006;50(6):642-645
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: It has been reported that spinal anesthesia has a sedative effect and so this decreases the hypnotic requirement of intravenous anesthetic. Therefore, we have conducted a prospective randomized study to investigate the effect of the spinal anesthesia level on the hypnotic requirements for conscious sedation. METHODS: Forty adult patients were scheduled to undergo spinal anesthesia, and they were randomly allocated to one of the two groups. After subarachnoid injection of 0.5% hyperbaric bupivacaine 16 mg, the patients in group 1 and group 2 were maintained in a reversed Trendelenburg position and a Trendelenburg position, respectively. After fifteen minutes, the target controlled infusion of propofol was started for achieving a target concentration of 1 microgram/ml, and the mean BIS for 1 min was checked after an effect site concentration (Ce) of 1 microgram/ml was reached. The target controlled infusion of propofol was restarted at a target concentration (Tc) of 1.5 microgram/ml, and the mean BIS for 1 min was checked after the Ce level of 1.5 microgram/ml was reached. RESULTS: The mean BIS at 1 microgram/ml Ce was 90.0 +/- 8.5 and 77.8 +/- 10.3 in group 1 and group 2, respectively. The mean BIS at 1.5 g/ml Ce was 73.6 +/- 19.4 and 60.0 +/- 13.1, respectively. CONCLUSIONS: There was a significant difference in the requirements of propofol for conscious sedation between the below T12 block group and the above T4 block group.
