Studies on chemical constituents from Isodon eriocalyx distributed in Hezhang
10.7501/j.issn.0253-2670.2019.10.007
- Author:
Jiang-Hai YE
1
Author Information
1. Guizhou University of Traditional Chinese Medicine
- Publication Type:Journal Article
- Keywords:
5,4’-dihydroxy-6,7-dimethoxy flavone;
Flavone;
Isodon eriocalyx (Dunn) Haral.;
Maoecrystal;
Rabdosia (Bl.) Hassk.;
Vitexin
- From:
Chinese Traditional and Herbal Drugs
2019;50(10):2296-2301
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the chemical constituents of Isodon eriocalyx. Methods The chemical constituents were isolated and purified by chromatography with silica gel, Sephadex LH-20 and semi-preparative HPLC, and their structures were identified by analysis of spectroscopic data and physicochemical properties as well as relevant references. Results :A total of 20 constituents were isolated from I. eriocalyx, plant material extracted with ethyl aceta, and they were elucidated as maoecrystal D (1), isothymusin (2), coetsoidin A (3), maoecrystal A (4), 5,4’-dihydroxy-6,7-dimethoxy flavone (5), vitexin (6), α-amyrin (7), β-daucosterol (8), odinicin (9), cirsimaritin (10), maoecrystal N (11), epi-macoecrystal P (12), pimaric acid (13), laxiflorin R (14), enmelol (15), maoecrystal B (16), pectolarigenin (17), neolaxiflorin V (18), eriocalyxin A (19), and neorabdosin (20). Conclusion: Compounds 2, 5-7, 13-15, 17, 18 are isolated from this plant for the first time, and compounds 5 and 6 are isolated from the plants of Isodon for the first time.
