A new dammarane-tye triterpenoid saponin from roots of Panax notoginseng
10.7501/j.issn.0253-2670.2019.10.003
- Author:
Kai-Ling NI
1
Author Information
1. Mudanjiang Youbo Pharmaceutical Company
- Publication Type:Journal Article
- Keywords:
20(S)-protopanaxatriol;
Dammarane;
Ginsenoside Rk3;
Notoginsenoside P1;
Notoginsenoside T5;
Panax notoginseng (Burk.) F. H. Chen;
Triterpenoid saponins
- From:
Chinese Traditional and Herbal Drugs
2019;50(10):2273-2278
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the minor triterpenoid saponins from the roots of Panax notoginseng, which provided basis for the systematic research, quality control and safety evaluation of P. notoginseng. Methods The compounds were isolated and purified by MCI resin, ODS, along with Preparative-HPLC, and the structures were identified by spectroscopic analysis, and comparing with the pubished literature values. Results: Twelve monomeric compounds isolated from the roots of P. notoginseng, were identified as notoginsenoside P1 (1), notoginsenoside T5 (2), ginsenoside Rk3 (3), ginsenoside Rh4 (4), notoginsenoside T3 (5), 20(S)-protopanaxatriol (6), dammar 20 (21),24-diene-3β,6α,12β-triol (7), ginsenoside Rg3 (8), gypenoside XIII (9), ginsenoside Rk1 (10), ginsenoside Rg5 (11), and 20 (S)-ginsenoside Rh2 (12). Conclusion: Compound 1 is a new dammarane-type triterpenoid saponin
