Optimization of processing technology of Sarcandra glabra based on multi-index evaluation method
10.7501/j.issn.0253-2670.2019.12.019
- Author:
Rou WEN
1
Author Information
1. School of Pharmacy, Jiangxi University of Traditional Chinese Medicine
- Publication Type:Journal Article
- Keywords:
Analytic hierarchy process;
Astilbin;
Caffeic acid;
Central composite design-response surface methodology;
Chlorogenic acid;
Cryptochlorogenic acid;
Isofraxidin;
Multi-index evaluation;
Neochlorogenic acid;
Rosmarinic acid;
Sarcandra glabra (Thunb.) Nakai
- From:
Chinese Traditional and Herbal Drugs
2019;50(12):2868-2875
- CountryChina
- Language:Chinese
-
Abstract:
Objective: Analytic hierarchy process (AHP) was used to establish a comprehensive evaluation method of multiple indexes of traditional Chinese medicine, and the best processing technology of Sarcandra glabra was optimized. Methods: On the basis of single factor experiment, the comprehensive score of neochlorogenic acid, chlorogenic acid, cryptochlorogenic acid, caffeic acid, isofraxidin, astilbin and rosmarinic acid content was used as evaluation index by AHP, and drying temperature and drying time were used as influencing factors. The purification process of S. glabra leaves was determined by single factor investigation. Taking soaking time, soaking time, cutting length and drying temperature as influencing factors, the optimal cutting process of S. glabra stems was optimized by central composite design-response surface method. Multi-index analytic hierarchy process (AHP) was used to analyze and verify the optimal process. Results: The best processing technology of S. glabra stems was as follows: stem Rob water washed once, soaked in 12 times of water for 1 h, moistened and softened for 3 h, cut into 15 mm segments after taking out, and baked at 50 ℃ for 2 h; The processing method of leaves was as follows: leaf Rob water washed once and dried at 50 ℃ for 4 h; Then mixed the processed stems and leaves of S. glabra at 2:1. The deviation between the verification value and the prediction value of the comprehensive score of the optimal S. glabra stem by softening and cutting method was 4.70%. Conclusion: The processing technology is simple, stable and feasible. The obtained parameters can provide scientific basis for the research and production of S. glabra, and AHP can provide reference for the multi-index evaluation of traditional Chinese medicine.
