Research progress in Atractylodes macrocephala and predictive analysis on Q-marker
10.7501/j.issn.0253-2670.2019.19.031
- VernacularTitle: 白术研究进展及其质量标志物(Q-marker)的预测分析
- Author:
Zhao-Min YAO
1
Author Information
1. School of Pharmacy, Anhui University of Traditional Chinese Medicine
- Publication Type:Journal Article
- Keywords:
Atractylodes macrocephala Koidz.;
Biosynthetic pathway;
Chemical substances basis;
Quality control;
Quality markers
- From:
Chinese Traditional and Herbal Drugs
2019;50(19):4796-4807
- CountryChina
- Language:Chinese
-
Abstract:
To study the quality marker (Q-marker) of Atractylodes macrocephala based on the concept, standard, and research model of Q-marker. The chemical constituents of A. macrocephala were identified by UPLC-Q-TOF-MS/MS. The source and specificity of chemical constituents were confirmed by analyzing biosynthetic pathway and component specificity. The major effective components were clarified through efficacy, drug property, and correlation analysis of chemical constituents. The possible Q-markers of A. macrocephala are estimated based on the results of the study.
