Research progress on chemical constituents and biological activities of Aphanamixis grandifolia
10.7501/j.issn.0253-2670.2019.22.033
- Author:
Yan-Wu CHEN
1
Author Information
1. College of Traditional Chinese Medicine, Yunnan University of Chinese Medicine
- Publication Type:Journal Article
- Keywords:
Antibacterial activities;
Antineoplastic activities;
Aphanamixis grandifolia Bl.;
Insecticidal activities;
Limonoids;
Terpenoids
- From:
Chinese Traditional and Herbal Drugs
2019;50(22):5621-5631
- CountryChina
- Language:Chinese
-
Abstract:
Aphanamixis grandifolia, a perennial herb of genus Aphanamixis (Meliaceae), has the effect of relaxing sinew and activating collaterals, dredging arthralgia, expelling wind-evil and removing wetness, etc. Previous phytochemical investigations on this plant resulted in the isolation of various terpenoid derivatives, including limonoids, tirucallane-type, dammarane-type, and cycloartane-type triterpenoids, as well as diterpenoids and sesquiterpenoids. Moreover, bioactivities of those compounds were evaluated, which displayed extensive biological properties, such as antibacterial, insecticidal, antineoplastic, anti-inflammatory, antimalarial, and antibacterial activities, etc. In this paper, the systematic classification, chemical constituents, and biological activities of A. grandifolia were summarized. It may provide the reference for the further studies of this plant.
