Research progress on CYP450 involved in medicinal plant triterpenoid biosynthesis
10.7501/j.issn.0253-2670.2019.22.031
- Author:
Ling-Ying ZHU
1
Author Information
1. College of Pharmaceutical Science, Yunnan University of Chinese Medicine
- Publication Type:Journal Article
- Keywords:
Biosynthesis;
Cytochrome P450;
Gene function;
Medicinal plant;
Triterpenoids
- From:
Chinese Traditional and Herbal Drugs
2019;50(22):5597-5610
- CountryChina
- Language:Chinese
-
Abstract:
Triterpenoids are active constituents of many medicinal plants. The biosynthetic pathways of triterpenes have been fully studied and significant progress has been made. CYP450s are mainly involved in the post-modification process of triterpenoids biosynthesis, which plays a key role in the diversity of triterpenoids. Currently, a lot of CYP450s, which related to the biosynthesis of triterpenoids, have been cloned from many plants. In this paper, CYP450s involved in the biosynthesis of triterpenoids were reviewed, which provided a reference for the analysis of the biosynthetic pathway of triterpenoids and the functional study of CYP450s.