Chemical constituents from rhizome of Tripterygium hypoglaucum
10.7501/j.issn.0253-2670.2019.22.002
- Author:
Qiang SONG
1
Author Information
1. College of Pharmacy, Nanjing University of Chinese Medicine
- Publication Type:Journal Article
- Keywords:
3,4-dimethoxyphenol;
3β-acetoxy oleanolic acid;
Diterpene;
Physcion;
Tripterone;
Tripterygium hypoglaucum (Lévl.) Hutch;
Triptobenzene B
- From:
Chinese Traditional and Herbal Drugs
2019;50(22):5395-5399
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the chemical constituents from the rhizome of Tripterygium hypoglaucum. Methods: The concrete exacted by 95% ethanol from the rhizome of T. hypoglaucum was isolated and purified by chromatography on silica gel column chromatography, gel column chromatography, MPLC, etc. The structures of the chemical constituents were elucidated by means of NMR, MS, etc. Results: Twelve compounds were isolated and identified as 3β-hydroxy-4-hydroxymethyl-abieta-8,11,13-trien-7-one (1), 3β-acetoxy oleanolic acid (2), physcion (3), canophyllal (4), chrysophenol (5), quinone 21 (6), tripterifordin (7), triptobenzene B (8), 3,4-dimethoxyphenol (9), integracin A (10), celastrol (11), and β-sitosterol (12). Conclusion: Compound 1 is a new diterpene named tripterone, compounds 8-10 are isolated from this plant for the first time.
