Relationship between types of abdominal obesity and interventricular septal hypertrophy in hypertension patients
- Author:
Hao YU
1
Author Information
1. Department of Hypertension and Endocrinology, Daping Hospital, Third Military Medical University
- Publication Type:Journal Article
- Keywords:
Hypertension;
Intra-abdominal fat;
Obesity;
Thickness;
ventricular septal
- From:
Medical Journal of Chinese People's Liberation Army
2012;37(11):903-906
- CountryChina
- Language:Chinese
-
Abstract:
Objective To illustrate the relationship between abdominal fat accumulation and cardiac remodeling in hypertension patients. Methods Visceral fat area (VA) and substantial fat area (SA) were assessed by CT in 380 hypertensive patients (male 198, female 182) with an age range of 21-83 years during the period of Jan 2006 to Dec 2008, and their blood pressure, waist circumference (WC), body mass index (BMI), interventricular septum thickness (IVST) were measured at the same time. The patients were divided into 4 groups according to their VA and WC, namely visceral fat obesity (VFO), pseudo-VFO, masked visceral fat obesity (MVFO), and non-obesity; intra-abdominal fat normal group (VA normal), intra-abdominal fat accumulation group (IFA); interventricular septum thickening group, and normal group. The differences in IVST, SA, VA, VA/ SA, WC and BMI were observed between the groups. Results The values of WC, VA, BMI, VA/SA were significantly higher in interventricular septum thickening group than in normal group, while the SA was significantly lower than that in normal group, and the difference was statistically significant (P<0.05). IVST, WC, BMI, VA and VA/SA were significantly higher in IFA group than in VA normal group, while SA was obviously higher in VA normal group, and showed statistically significant difference (P<0.05). IVST and VA were significantly higher in VFO group than in other groups (P<0.05), and the VA/SA was significantly lower in VFO group than in MVFO group (P<0.05); the IVST and VA in MVFO group were significantly higher than those in pseudo-VFO group and non-obesity group (P<0.05). The SA in pseudo-VFO group was significantly higher than that in VFO, MVFO and non-obesity groups (P<0.05), however, there was no statistically significant difference in IVST when compared with non-obesity group. Logistic correlation analysis showed VA/SA, VA and WC were the risk factors leading to ventricular septal hypertrophy. Conclusions Masked abdominal obesity is significantly related to septal hypertrophy in hypertension, and VA/SA is an important risk factor for ventricular septal hypertrophy.
