Sarcomatoid carcinoma of the small intestine: a rare and highly aggressive tumor.
10.4174/jkss.2012.83.5.321
- Author:
Sang Eok LEE
1
;
Shin Young PARK
Author Information
1. Department of Surgery, Konyang University Hospital, Daejeon, Korea.
- Publication Type:Case Report
- Keywords:
Small intestine;
Sarcomatoid carcinoma
- MeSH:
Abdominal Pain;
Actins;
Desmin;
Hemorrhage;
Humans;
Immunohistochemistry;
Intestine, Small;
Keratins;
Middle Aged;
Mitosis;
Muscle, Smooth;
Necrosis;
Prognosis;
Vimentin
- From:Journal of the Korean Surgical Society
2012;83(5):321-324
- CountryRepublic of Korea
- Language:English
-
Abstract:
Sarcomatoid carcinoma of the small intestine is an extremely rare malignant neoplasm that usually has a poor prognosis. We report a case of sarcomatoid carcinoma arising in the small intestine in a 62-year-old man who was hospitalized for abdominal pain. Computed tomography revealed wall thickening of the small intestine. The resected specimen showed a gray-whitish solid mass with hemorrhage and necrosis. Microscopically, the tumor was composed of pleomorphic spindle and discohesive polygonal cells with frequent mitosis. No carcinomatous component was recognized. Immunohistochemistry revealed coexpression of cytokeratin and vimentin by the tumor cells, whereas expressions of C-kit, CD34, HMB-45, smooth muscle actin, and desmin were negative. The diagnosis was sarcomatoid carcinoma of the small intestine.
