Correlation study of intra-abdominal fat accumulation and ambulatory blood pressure
- Author:
Li ZHANG
1
Author Information
1. Department of Cardiology, First Affiliated Hospital, Luzhou Medical College
- Publication Type:Journal Article
- Keywords:
Ambulatory blood pressure monitoring;
Hypertension;
Intra-abdominal fat;
Obesity
- From:
Medical Journal of Chinese People's Liberation Army
2012;37(5):412-415
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the influence of intra-abdominal fat (IAF) accumulation on ambulatory blood pressure (ABP). Methods Four hundred and forty-eight hospitalized patients with cardiovascular and metabolic diseases, including 235 males and 213 females, aged 20-85 (55±12) years old, were enrolled in this study. The abdominal fatty thickness was measured with B-mode ultrasound. Simultaneously the patient received 24hABP monitoring. The patients were divided into excessive IAF group, normal group, and quintile subgroups according to the cut-off points (male 38.5mm, female 34.7mm) for observing the difference in indexes of ambulatory blood pressure between different groups/subgroups. Results The 24h mean systolic BP (24hMSBP), 24h mean BP (24hMBP), 24h mean diastolic BP (24hMDBP), daytime MSBP (dMSBP), daytime MBP (dMBP), daytime MDBP (dMDBP), nighttime MSBP (nMSBP), nighttime MBP (nMBP), night MDBP (nMDBP) were significantly higher in the excessive IAF group than in the normal group (P < 0.05). However, the elevation of ABP was not a simple gradual linear elevation corresponding to a gradual increase in IAF thickness, but manifested an approximately U-shaped trend. Pearson correlation analysis showed IAF thickness was positively correlated with all the indexes of 24hABP, while partial correlation analysis after adjustment for age and sex showed IAF thickness was positively correlated with 24hSBP, 24hMBP, dMBP and nMBP. Conclusion The relationship between IAF thickness and ABP presents a U-shaped curve, which may provide an enlightenment in controlling blood pressure by weight loss in clinical work.
