Contrast-induced acute kidney injury
10.11855/j.issn.0577-7402.2014.04.01
- Author:
Ya-Ling HAN
1
Author Information
1. Department of Cardiology, General Hospital of Shenyang Command
- Publication Type:Journal Article
- Keywords:
Acute;
Contrast media;
Hydroxymethylglutaryl-Coa reductase inhibitors;
Renal insufficiency
- From:
Medical Journal of Chinese People's Liberation Army
2014;39(4):255-258
- CountryChina
- Language:Chinese
-
Abstract:
Contrast-induced acute kidney injury (CIAKI), known as the most important complication after exposure to intravascular iodine based contrast agents, has attracted increasing attention with the development of cardiac intervention in recent years. CIAKI is harmful as it increases the risk of renal failure and death, prolongation of hospitalization time, and increase in expenditure. Moreover, lack of obvious clinical manifestation makes CIAKI more easily neglected by clinicians. Preceding risk assessment and giving prophylactic measures to high risk patients may lower the incidence of CIAKI. Continuous renal function monitoring after intervention procedure is helpful to detect CIAKI. Hydration has been proved to be effective for the prevention of CIAKI. However, the affect of other medication has not been well evaluated up to now. A multicenter, randomized and controlled study, performed in union in 53 domestic hospitals with the same protocol, demonstrated that short-term statin therapy during perioperative period of invasive cardiovascular procedure can effectively reduce the incidence of CIAKI. It may give us a new strategy to prevent CIAKI.
