Effect of xiao-tan-jie-yu prescription on sleep quality of soldiers acute exposure to high altitude
10.11855/j.issn.0577-7402.2016.10.15
- Author:
Yu-Xing YANG
1
Author Information
1. Department of Traditional Chinese Medicine
- Publication Type:Journal Article
- Keywords:
Altitude;
Military personnel;
Sleep disorders;
Xiao-tan-jie-yu prescription
- From:
Medical Journal of Chinese People's Liberation Army
2016;41(10):869-873
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the efficacy of Xiao-tan-jie-yu prescription (XTJYF) on sleep quality of the soldiers who acutely exposed to western area of high altitude. Methods In this prospective, completely randomized, parallel, placebocontrolled study, 550 soldiers acutely exposed to western area of high altitude were investigated by the Pittsburgh Sleep Quality Index (PSQI), 100 soldiers with sleep disorder were selected and divided into two groups (50 each): treatment group received TCM XTJYF therapy and control group was treated with placebo. After 2 weeks' treatment, PSQI total score and respective factor scores before and after treatment were assessed, and clinical therapeutic efficacy and adverse reactions were observed. Results The PSQI total score and respective factor scores of these soldiers were significantly higher than those of normal adults, but significantly lower than those of insomnia patients, while their sleep disorder factor score was significantly higher compared with insomnia patients. XTJYF reduced the total score and some factor scores (subjective sleep quality, time for initiating sleep, total sleep time, and sleep efficiency) for PSQI in the soldiers with sleep disorder, and the overall response rate was 91.49% which is higher than those in the placebo control group (P<0.05 or 0.01), without toxic side effects. Conclusions The sleep quality of soldiers who acutely exposed to western area of high altitude in China is not high, and XTJYF may safely and effectively improve the sleep quality.
