Diagnosis, treatment and prognosis of neuroendocrine tumor in stomach and duodenum
10.11855/j.issn.0577-7402.2016.03.12
- Author:
Xiang-Yao WANG
1
Author Information
1. Department of Gastroenterology, General Hospital of PLA
- Publication Type:Journal Article
- Keywords:
Clinical;
Early diagnosis;
Neuroendocrine tumors;
Pathology;
Prognosis
- From:
Medical Journal of Chinese People's Liberation Army
2016;41(3):233-237
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinicopathological characteristics and prognosis of patients with neuroendocrine tumor in stomach and duodenum for early diagnosis. Methods The clinical, endoscopic and pathological data of 20 patients admitted to the PLA General Hospital from Jan. 2012 to Jan. 2015 and diagnosed as gastric and duodenal neuroendocrine tumor were collected for retrospective analysis. The histopathological classification of the disease was made according to the WHO 2010 Classification of the Neuroendocrine Neoplasms. Result Ten male and 10 female patients aged between 35 and 77 (mean 55.5±10.6) years old were recruited in the present study. Tumor located in the stomach in 13 cases, and in duodenum in 7 cases. The maximum diameter of the tumor was 0.2-2.5cm. Endoscopic features included polypoid protrusion, hemispheric submucosal protrusion, and mucosal erosion. All the patients were treated endoscopically, among them, four patients were treated with electrocoagulation and electrosection, 10 by endoscopic resection (EMR), and 6 by endoscopic submucosal dissection (ESD). In one patient, surgical excision was done after ESD. Biopsy under gastroscopy and endoscopic ultrasonography were conducive to the diagnosis and treatment. According to the histopathological classification, 19 cases were classified as NET grade 1, and another one as NET grade 2. The follow-up study showed no metastasis and recurrence. Conclusions The early diagnosis and treatment for gastric and duodenal neuroendocrine tumor can lead to satisfactory results.
