A Case of Colchicine Intoxication Presenting as Acute Gastroenteritis.
- Author:
Ji Yun AHN
1
;
You Dong SOHN
;
Hyuk Sool KWON
;
Hee Chol AHN
Author Information
1. Department of Emergency Medicine, College of Medicine, Hallym University, Anyang, Korea. gsemdr68@hallym.or.kr
- Publication Type:Case Report
- Keywords:
Colchicine;
Poisoning;
Gastroenteritis;
Pancreatitis
- MeSH:
Alopecia;
Bone Marrow;
Colchicine;
Familial Mediterranean Fever;
Female;
Gastroenteritis;
Gout;
Humans;
Middle Aged;
Pancreatitis
- From:Journal of The Korean Society of Clinical Toxicology
2008;6(2):138-141
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
A 47-year-old woman ingested about 12 mg of colchicine with suicidal intent. Colchicine, a highly poisonous alkaloid, is a commonly used treatment for gout, Bechet's disease, and familial Mediterranean fever. Despite the knowledge of its side effects, the risk of a significant overdose is under-appreciated. She suffered from acute multisystem toxicity, including gastrointestinal disorders, bone marrow suppression, alopecia, and probable pancreatitis, but she ultimately recovered with supportive therapy. We report a case of acute colchicine toxicity from a single overdose with a review of the literature.
