Clinical analysis of 16 patients with primitive neuroectodermal tumors
- Author:
Rui WEI
1
Author Information
1. Department of Oncology
- Publication Type:Journal Article
- Keywords:
Diagnosis;
Nerve neoplasms;
Treatment outcome
- From:
Tumor
2007;27(10):835-837
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To analyze the pathological features, diagnosis, and treatment of primitive neuroectodermal tumors (PNET). Methods: The clinical data from 16 PNET patients were summarized and analyzed. There were 4 cases with the tumor located in brain, 4 cases in mediastina, 2 cases in orbit, 2 cases in thoracic cord, 2 cases in pelvic limb, 1 case in neck, 1 case in belly cavity. Six patients received surgical resection alone (S) and ten patients received chemotherapy plus radiotherapy after surgery (S + R + C). Results: There were 14 patients died. The median survival time was 22 months. The median survival time was 13 months for S group and 28 months for S + R + C group, respectively. The difference was significant (P =0.0194). Conclusion: PNET is one kind of highly malignant neuroepithelioma with great aggressive ability. Surgery combined with radiotherapy and chemotherapy was the best choice.
