Incidental prostate cancer after transurethral resection of prostatea - A retrospective analysis of 24 cases
- Author:
Jian KANG
1
Author Information
1. Department of Urology
- Publication Type:Journal Article
- Keywords:
Combined modality therapy;
Follow-up studies;
Prostate neoplasm;
Transurethral resection of prostate
- From:
Tumor
2007;27(12):1003-1005
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To summarize and analyze clinical data of incidental prostate cancer (IPCa) after transurethral resection of prostate. Methods: We followed up 2 815 prostate hyperplasia patients for two years. The survival rate, prostate specific antigen (PSA) progression, and therapeutic method were summarized retrospectively. Results: The occurrence rate of incidental prostate cancer was 0.8% (24/ 2 815), involving 9 cases at stage T1a and 15 cases at stage T1b. The preoperative PSA value was (2.61 ± 1.02) μg/L for T1a patients and (2.89 ± 0.92) μg/L for T1b patients. There was no significant difference between the two groups (P = 0.12). However, postoperative Gleason score was (4.52 ± 0.49) and (7.15 ± 1.22) for the patients at T1a and T1b stage, respectively. The difference was significant (P = 0.032). Among the 9 patients at T1a stage, 4 patients selected watchful waiting, 4 accepted endocrinal therapy, one case underwent radical prostectomy. With regard to the 15 cases at T1b stage, 3 selected watchful waiting, 11 patients accepted endocrinal therapy and one case underwent radical prostectomy. After 2-year follow-up, no tumor-related death occurred in these 2 groups. Conclusion: The Gleason score was higher at stage T1b than that at stage T1a. The patients had good surviving rate during 2-year follow-up period no matter which kind of treatment they accepted. Long-term outcome of IPCa is still under further investigation. Re-staging was quite important for guiding treatment and predicting prognois.
