Clinical and Radiological Characteristics of Ischemic Stroke in the 80 Year-Old or Older: A Single Center Study.
- Author:
Eun Ye LIM
1
;
Min Jeong WANG
;
Hyung Eun PARK
;
Eu Jene CHOI
;
Ji Yeon LEE
;
Woojoon KIM
;
A Hyun CHO
Author Information
1. Department of Neurology, Yeouido St. Mary's Hospital, The Catholic University of Korea College of Medicine, Seoul, Korea. ahyun@catholic.ac.kr
- Publication Type:Original Article
- Keywords:
Ischemic stroke;
Elderly;
Clinical outcome;
Diffusion-weighted imaging
- MeSH:
Aged;
Humans;
Infarction;
Male;
Multivariate Analysis;
National Institutes of Health (U.S.);
Risk Factors;
Stroke*
- From:Journal of the Korean Neurological Association
2013;31(4):234-238
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: The risk profiles and stroke presentations may differ between elderly stroke patients and their younger counterparts. The most appropriate stroke-management regime for a better outcome can only be achieved with knowledge of the characteristics of elderly stroke patients. This study compared the clinical and radiological characteristics of elderly (> or =80 years) ischemic stroke patients with those aged <80 years. METHODS: Consecutive acute ischemic stroke patients were enrolled. The following parameters were obtained for each patient: clinical variables [i.e., risk factors, initial National Institutes of Health Stroke Scale (NIHSS) score, mode of onset, in-hospital complications, and modified Rankin scale (mRS) score at 3 months], radiological variables, and clinicoradiological discrepancies. RESULTS: Of the 436 enrolled patients, 60 (13.8%) were elderly. The proportion of men was lower among the elderly than among those patients aged >80 years (40.0% vs. 63.3%; p=0.001), while their initial NIHSS score was higher (median, 4 vs. 3; p=0.033). Furthermore, an unclear stroke onset (46.4% vs. 32.8%; p=0.049) and clinicoradiological discrepancies (13.8% vs. 5.7%; p=0.044) were more common among the elderly. The proportions of subjects with stroke of undetermined cause (30.0% vs. 18.0%; p=0.019) and multiple circulation infarctions (23.3% vs. 12.6%, p=0.030) were higher among the elderly. A favorable outcome (mRS score of 0 or 1) was more common in the younger stroke patients (57.5% vs. 25.9%, p<0.0001). Multivariate analysis revealed that younger age, male gender, and initial stroke severity were significantly associated with a favorable outcome. CONCLUSIONS: These results indicate that stroke presentation in the elderly differs from that of their younger counterparts in terms of clinical and radiological variables.
