Evaluation on the operative situations of radical hysterectomy in 440 cervical cancer patients
10.3781/j.issn.1000-7431.2008.11.018
- Author:
Jing-Hai GAO
1
Author Information
1. Obstetrics and Gynecology Hospital of Fudan University
- Publication Type:Journal Article
- Keywords:
Prognosis;
Surgical procedure, operative;
Uterine cervical neoplasms
- From:
Tumor
2008;28(11):986-989
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To analyze the clinical and operative situations of radical hysterectomy in 440 cervical cancer patients. Methods: The clinical and operative situations were retrospectively evaluated in 440 cervical cancer patients. All the patients received radical hysterectomy and pelvic lymphadenectomy by the Wertheim-Okabayashi procedure. Results: The average age of the patients was 43.9 (21-78) years old and the mean body mass index (BMI) was 23.2(15.8-47.3) kg/m2. Histologic classification included: 353 cases (80.2%) of squamous cell carcinoma, 56 (12.8%) cases of adenocarcinoma, 20 (4.6%) cases of adeno-squamous carcinoma, and 11 (2.5%) cases of other types. According to International Federation of Gynecology and Obstetrics (FIGO) staging standard, 314 (71.4%) cases were at stage I and 126 (28.6%) cases were at stage II, respectively. The mean operation time was 221 (90-410) min and the average blood loss was 697 (80-2 300) mL. One hundred and forty eight patients received blood transfusion with an average volume of 825 (200-2 300) mL. 87 patients (19.8%) had lymph node metastasis, and the average number of positive lymph nodes was 2.1(1-5). 83 patients (18.9%) had lymph-vascular space involvement (LVSI). The patients stayed in hospital for 26(9-57) days. Post surgery complications occurred in 145 women (32.9%). They included urine retention, wound infection, lymphocyst, and deep-vein thrombosis (DVT). One hundred and 25 patients had more than 100 mL of post-void residual urine volume (PVR), and 73 patients got fever after surgery. Conclusions: Radical hysterectomy and pelvic lymphadenectomy performed in our hospital achieved better clinical outcome in the treatment of cervical cancer.
