Progress in the research of Myc and its related microRNAs in tumors
10.3781/j.issn.1000-7431.2011.02.016
- Author:
Yong-Chao LIU
1
Author Information
1. Department of Urology
- Publication Type:Journal Article
- Keywords:
Genes, myc;
MicroRNAs;
Neoplasms;
Tumor stem cells
- From:
Tumor
2011;31(2):169-172
- CountryChina
- Language:Chinese
-
Abstract:
Myc is an important oncogene family, whose members can interact with microRNAs (miRNAs) as oncogene or tumor suppressor. The complicated regulatory network between Myc and miRNAs is crucial for tumorigenesis. This interaction was also reported in many studies involving stem cells, and it opened a new chapter for current cancer research. This review is about the progress in the research of Myc and its related miRNAs as oncogene or tumor suppressor, as well as their roles in cancer stem cells.